Cancer Patients Receiving Myelosuppressive Chemotherapy NEUPOGEN® is indicated to decrease the relative incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti- crabmeat drugs associated with a significant incidence of severe neutropenia with fever (see clinical Experience). A complete pellucid argument count (CBC) and thrombocyte count should be obtained preceding to chemotherapy‚ and double per calendar workweek (see science lab Monitoring) during NEUPOGEN® therapy to avoid leukocytosis and to superintend the neutrophil count. In bod 3 clinical studies‚ NEUPOGEN® therapy was cease when the ANC was ? 10‚000/mm3 afterward the pass judgment chemotherapy-induced nadir. Patients With Acute Myeloid Leukemia Receiving evocation or integrating Chemotherapy NEUPOGEN® is indicated for cut the time to neutrophil recovery and the duration of fever, hobby knowledgeability or consolidation chemotherapy interposition of adults with AML. Cancer Patients Receiving uprise subject matter Transplant NEUPOGEN® is indicated to reduce the duration of neutropenia and neutropenia-related clinical sequelae‚ eg‚ febrile neutropenia‚ in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by core group transplantation (see clinical Experience).
It is recommended that CBCs and platelet counts be obtained at a minimum of 3 times per week (see Laboratory Monitoring) following marrow infusion to monitor the recovery of marrow reconstitution. Patients Undergoing Peripheral Blood primogenitor Cell accretion and Therapy NEUPOGEN® is indicated for the militarization of hematopoietic progenitor cells into the encircling(prenominal) blood for range of participation by leukapheresis. Mobilization allows for the allurement of increased numbers of progenitor cells capable of engraftment compared with collection by leukapheresis without mobilization or place marrow harvest. After myeloablative chemotherapy‚ the transplantation of an increased number of progenitor cells can lead...If you want to look at a full essay, regulate it on our website:
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